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KMID : 0895820080180040063
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Journal of Oriental Rehabilitation Medicine
2008 Volume.18 No. 4 p.63 ~ p.72
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The Effect of Ecklonia Cava on Expressing of Blood Lipids and UCP-1 of Brown Adipose Tissue(BAT) in Zucker Rats
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Kim Hyun-Woo
Kim Ho-Jun
Lee Myeong-Jong
Park Young-Hoi
Keum Dong-Ho
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Abstract
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Objectives :This study was designed to examine the effect of Ecklonia cava on expressing of blood lipids and UCP-1 of brown adipose tissue(BAT) in zucker rats.
Methods :Experimental groups were divided into 3 groups: normal group, control group and sample group for 7 separate rats as expriment. Control and sample groups were genetrically modified obesity. All groups didn’t impose restrictions on food and water. And we gave a ecklonia cava to sample group for 6 weeks. Ecklonia cava was examined in effects of blood glucose, insulin concentration and UCP-1 in brown adipose tissue.
Results :1. Control and sample groups were increased in weight. But, sample group was decreased as compared to control group. 2. Sample group was decreased significantly as compared to control group with insulin concentration, HOMA, TG, FFA. 3. Sample group was increased significantly as compared to control group with UCP-1 mRNA.
Conclusion :Based on these results, it was proved that Ecklonia cava on obesity effects in decreasing blood lipids, increasing UCP-1 of brown adipose tissue.
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KEYWORD
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Ecklonia cava, UCP-1, Brown adipose tissue, Obesity, Blood lipid
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